Maria Manifava Selected Research

Proteasome Endopeptidase Complex (Proteasome)

1/2022

Inhibition of the SEC61 translocon by mycolactone induces a protective autophagic response controlled by EIF2S1-dependent translation that does not require ULK1 activity.

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Maria Manifava Research Topics

Disease

6	Starvation 01/2021 - 08/2008
2	Pancreatic Neoplasms (Pancreatic Cancer) 08/2023 - 01/2023
2	Neoplasms (Cancer) 08/2023 - 01/2023
1	Sarcoma (Soft Tissue Sarcoma) 08/2023
1	Hypoxia (Hypoxemia) 01/2023
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2023
1	Necrosis 01/2022
1	Buruli Ulcer 01/2022
1	Virus Diseases (Viral Diseases) 11/2011
1	Infections 11/2011

Drug/Important Bio-Agent (IBA)

6	Proteins (Proteins, Gene)FDA Link 08/2023 - 08/2008
3	phosphatidylinositol 3-phosphateIBA 01/2022 - 11/2008
2	UbiquitinIBA 08/2023 - 01/2022
2	Phosphates (Orthophosphate)IBA 01/2022 - 11/2011
2	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2022 - 11/2011
2	Amino Acids FDA Link 11/2008 - 08/2008
1	Cullin Proteins (Cullins)IBA 08/2023
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 08/2023
1	Ligases (Synthetase)IBA 08/2023
1	phosphatidylethanolamineIBA 01/2023
1	bafilomycin A1IBA 01/2022
1	mycolactoneIBA 01/2022
1	CalciumIBA 01/2022
1	Carrier Proteins (Binding Protein)IBA 01/2022
1	Chloroquine (Aralen)FDA LinkGeneric 01/2022
1	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 01/2022
1	ExotoxinsIBA 01/2022
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2022
1	paraform (paraformaldehyde)IBA 01/2022
1	Phosphotransferases (Kinase)IBA 01/2022
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2022
1	Green Fluorescent ProteinsIBA 01/2022
1	Activating Transcription Factor 4IBA 01/2022
1	Prokaryotic Initiation Factor-2IBA 01/2022
1	Ivermectin (Mectizan)FDA Link 01/2021
1	WortmanninIBA 09/2013

Therapy/Procedure

1	Therapeutics 08/2023
1	Cell- and Tissue-Based Therapy (Cell Therapy) 08/2023
1	Drug Therapy (Chemotherapy) 01/2023